Researchers from a Université de Bordeaux in France wrote “Magnetic field triggered drug release from polymersomes for cancer therapeutics” for the August 2013 issue of the Journal of Controlled Release. In this article, the scientists used Spectrum dialysis tubing to purify polymersome nanoparticles.
The biopharmaceutical industry is increasingly interested in the development of drug delivery vehicles using nanotechnology with the intent to reduce side effects and increase drug efficacy. In this paper, the scientists developed a “smart” polymersome for drug delivery, with the capability to react to internal and external stimuli in order for drugs to reach their intended targets.
Abstract: Local and temporal control of drug release has for long been a main focus in the development of novel drug carriers. Polymersomes, which can load both hydrophilic and hydrophobic species and, at the same time, be tailored to respond to a desired stimulus, have drawn much attention over the last decade. Here we describe polymersomes able to encapsulate up to 6% (w/w) of doxorubicin (DOX) together with 30% (w/w) of superparamagnetic iron oxide nanoparticles (USPIO; γ-Fe2O3). Click here to read the article.
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