New! Tangential Flow Depth Filtration® Technology (TFDF®) for Bioreactor Perfusion. TFDF combines the advantages of tangential flow filtration (TFF) and depth filtration to minimize membrane fouling and maximize protein passage.

With Tangential Flow Depth Filtration Technology the hollow fiber membrane structure allows cells to be swept across filter surface and returned to the bioreactor. The thick fiber wall and large pore size distribution acts as a depth filter to trap cellular debris and minimize membrane fouling.

TFDF is provided in a sterile Pro-Connex® Flow Path strictly for Spectrum’s simple to use, low pressure, ready-to-operate KML® 100 and KPS® 600 TFF perfusion systems. Filters are available in the MiniKros® Sampler, MiniKros, and KrosFlo® sizes.